Publikace
- Gene Expression Profiling of 1alpha,25(OH)2D3 Treatment in 2D/3D Human Hepatocyte Models Reveals CYP3A4 Induction but Minor Changes in Other Xenobiotic-Metabolizing Genes2022 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Plzni
- 3 beta-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3 alpha-epimer by hepatic metabolism2020 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové, Přírodovědecká fakulta
- Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain2020 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové, Fakulta tělesné výchovy a sportu
- Stilbene compound trans-3,4,5,4'-tetramethoxystilbene, a potential anticancer drug, regulates constitutive androstane receptor (Car) target genes, but does not possess proliferative activity in mouse liver2019 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
- Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling2018 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
- Expression of organic cation transporter 1 (OCT1): unique patterns of indirect regulation by nuclear receptors and hepatospecific gene regulation2016 | Farmaceutická fakulta v Hradci Králové
- Chrysin, baicalein and galangin are indirect activators of the human constitutive androstane receptor (CAR)2015 | Farmaceutická fakulta v Hradci Králové
- Bioinformatic analysis of miRNAs targeting the key nuclear receptors regulating CYP3A4 gene expression: The challenge of the CYP3A4 "missing heritability" enigma2015 | Farmaceutická fakulta v Hradci Králové
- Nuclear receptors in regulation of biotransformation enzymes and drug transporters in the placental barrier2014 | Farmaceutická fakulta v Hradci Králové
- U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells2014 | Farmaceutická fakulta v Hradci Králové
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