Publikace
- Gene Expression Profiling of 1alpha,25(OH)2D3 Treatment in 2D/3D Human Hepatocyte Models Reveals CYP3A4 Induction but Minor Changes in Other Xenobiotic-Metabolizing Genes2022 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Plzni
- Transcriptional and post-transcriptional regulation of the pregnane X receptor: a rationale for interindividual variability in drug metabolism2021 | Farmaceutická fakulta v Hradci Králové
- Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver2019 | Farmaceutická fakulta v Hradci Králové, 3. lékařská fakulta
- Trans-resveratrol, but not other natural stilbenes occurring in food, carries the risk of drug-food interaction via inhibition of cytochrome P450 enzymes or interaction with xenosensor receptors2019 | Farmaceutická fakulta v Hradci Králové
- Steviol, an aglycone of steviol glycoside sweeteners, interacts with the pregnane X (PXR) and aryl hydrocarbon (AHR) receptors in detoxification regulation2017 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
- Expression of organic cation transporter 1 (OCT1): unique patterns of indirect regulation by nuclear receptors and hepatospecific gene regulation2016 | Farmaceutická fakulta v Hradci Králové
- The pregnane X receptor down-regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for ("squelching") SRC-1 coactivator2016 | Farmaceutická fakulta v Hradci Králové
- U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells2014 | Farmaceutická fakulta v Hradci Králové
- Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure2023 | Farmaceutická fakulta v Hradci Králové, 1. lékařská fakulta, Ústřední knihovna
- Expression dynamics of pregnane X receptor-controlled genes in 3D primary human hepatocyte spheroids2022 | Farmaceutická fakulta v Hradci Králové
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