Publikace
- The 3'-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids2020 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
- Trans-resveratrol, but not other natural stilbenes occurring in food, carries the risk of drug-food interaction via inhibition of cytochrome P450 enzymes or interaction with xenosensor receptors2019 | Farmaceutická fakulta v Hradci Králové
- 1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria2014 | Farmaceutická fakulta v Hradci Králové
- Nuclear receptors in regulation of biotransformation enzymes and drug transporters in the placental barrier2014 | Farmaceutická fakulta v Hradci Králové
- U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells2014 | Farmaceutická fakulta v Hradci Králové
- Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure2023 | Farmaceutická fakulta v Hradci Králové, 1. lékařská fakulta, Ústřední knihovna
- Gene Expression Profiling of 1alpha,25(OH)2D3 Treatment in 2D/3D Human Hepatocyte Models Reveals CYP3A4 Induction but Minor Changes in Other Xenobiotic-Metabolizing Genes2022 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Plzni
- Expression dynamics of pregnane X receptor-controlled genes in 3D primary human hepatocyte spheroids2022 | Farmaceutická fakulta v Hradci Králové
- Transcriptional and post-transcriptional regulation of the pregnane X receptor: a rationale for interindividual variability in drug metabolism2021 | Farmaceutická fakulta v Hradci Králové
- 3 beta-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3 alpha-epimer by hepatic metabolism2020 | Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové, Přírodovědecká fakulta
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