Publications
- Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure2023 | Faculty of Pharmacy in Hradec Králové, First Faculty of Medicine, Central Library of Charles University
- 3 beta-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3 alpha-epimer by hepatic metabolism2020 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové, Faculty of Science
- Trans-resveratrol, but not other natural stilbenes occurring in food, carries the risk of drug-food interaction via inhibition of cytochrome P450 enzymes or interaction with xenosensor receptors2019 | Faculty of Pharmacy in Hradec Králové
- A feasibility study of the toxic responses of human induced pluripotent stem cell-derived hepatocytes to phytochemicals2018 | Faculty of Pharmacy in Hradec Králové
- Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis2016 | Faculty of Pharmacy in Hradec Králové
- 2-(3-Methoxyphenyl)quinazoline Derivatives: A New Class of Direct Constitutive Androstane Receptor (CAR) Agonists2016 | Faculty of Pharmacy in Hradec Králové
- Laminin-511 and laminin-521-based matrices for efficient hepatic specification of human pluripotent stem cells2016 | Publication without faculty affiliation
- Glucocorticoid receptor regulates organic cation transporter 1 (OCT1, SLC22A1) expression via HNF4alpha upregulation in primary human hepatocytes2013 | Faculty of Pharmacy in Hradec Králové
- Gene Expression Profiling of 1alpha,25(OH)2D3 Treatment in 2D/3D Human Hepatocyte Models Reveals CYP3A4 Induction but Minor Changes in Other Xenobiotic-Metabolizing Genes2022 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Pilsen
- Expression dynamics of pregnane X receptor-controlled genes in 3D primary human hepatocyte spheroids2022 | Faculty of Pharmacy in Hradec Králové
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