Publications
- 3 beta-Isoobeticholic acid efficiently activates the farnesoid X receptor (FXR) due to its epimerization to 3 alpha-epimer by hepatic metabolism2020 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové, Faculty of Science
- Diazepam Promotes Translocation of Human Constitutive Androstane Receptor (CAR) via Direct Interaction with the Ligand-Binding Domain2020 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové, Faculty of Physical Education and Sport
- The 3'-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids2020 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Genetic Predispositions of Glucocorticoid Resistance and Therapeutic Outcomes in Polymyalgia Rheumatica and Giant Cell Arteritis2019 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové, Faculty of Mathematics and Physics
- Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver2019 | Faculty of Pharmacy in Hradec Králové, Third Faculty of Medicine
- Stilbene compound trans-3,4,5,4'-tetramethoxystilbene, a potential anticancer drug, regulates constitutive androstane receptor (Car) target genes, but does not possess proliferative activity in mouse liver2019 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling2018 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- A feasibility study of the toxic responses of human induced pluripotent stem cell-derived hepatocytes to phytochemicals2018 | Faculty of Pharmacy in Hradec Králové
- Iron depletion induces hepatic secretion of biliary lipids and glutathione in rats2017 | Faculty of Pharmacy in Hradec Králové, First Faculty of Medicine, Faculty of Medicine in Hradec Králové
- Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis2016 | Faculty of Pharmacy in Hradec Králové
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