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PharmDr. Tomáš Smutný Ph.D.
Academic staff at Faculty of Pharmacy in Hradec Králové
29 publications
Publications
publication
Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure
2023 |
Faculty of Pharmacy in Hradec Králové, First Faculty of Medicine, Central Library of Charles University
publication
Gene Expression Profiling of 1alpha,25(OH)2D3 Treatment in 2D/3D Human Hepatocyte Models Reveals CYP3A4 Induction but Minor Changes in Other Xenobiotic-Metabolizing Genes
2022 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Pilsen
publication
Sesquiterpenes Are Agonists of the Pregnane X Receptor but Do Not Induce the Expression of Phase I Drug-Metabolizing Enzymes in the Human Liver
2019 |
Faculty of Pharmacy in Hradec Králové, Third Faculty of Medicine
publication
Stilbene compound trans-3,4,5,4'-tetramethoxystilbene, a potential anticancer drug, regulates constitutive androstane receptor (Car) target genes, but does not possess proliferative activity in mouse liver
2019 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Iron depletion induces hepatic secretion of biliary lipids and glutathione in rats
2017 |
Faculty of Pharmacy in Hradec Králové, First Faculty of Medicine, Faculty of Medicine in Hradec Králové
publication
Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis
2016 |
Faculty of Pharmacy in Hradec Králové
publication
2-(3-Methoxyphenyl)quinazoline Derivatives: A New Class of Direct Constitutive Androstane Receptor (CAR) Agonists
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Expression of organic cation transporter 1 (OCT1): unique patterns of indirect regulation by nuclear receptors and hepatospecific gene regulation
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Chrysin, baicalein and galangin are indirect activators of the human constitutive androstane receptor (CAR)
2015 |
Faculty of Pharmacy in Hradec Králové
publication
The Aryl Hydrocarbon Receptor in the Human Placental Trophoblast: The Impact of Nutraceuticals and Natural Products
2015 |
Faculty of Pharmacy in Hradec Králové
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