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PharmDr. Tomáš Smutný Ph.D.
Academic staff at Faculty of Pharmacy in Hradec Králové
29 publications
Publications
publication
Transcriptional and post-transcriptional regulation of the pregnane X receptor: a rationale for interindividual variability in drug metabolism
2021 |
Faculty of Pharmacy in Hradec Králové
publication
The 3'-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids
2020 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling
2018 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Iron depletion induces hepatic secretion of biliary lipids and glutathione in rats
2017 |
Faculty of Pharmacy in Hradec Králové, First Faculty of Medicine, Faculty of Medicine in Hradec Králové
publication
Expression of organic cation transporter 1 (OCT1): unique patterns of indirect regulation by nuclear receptors and hepatospecific gene regulation
2016 |
Faculty of Pharmacy in Hradec Králové
publication
The pregnane X receptor down-regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for ("squelching") SRC-1 coactivator
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Chrysin, baicalein and galangin are indirect activators of the human constitutive androstane receptor (CAR)
2015 |
Faculty of Pharmacy in Hradec Králové
publication
Bioinformatic analysis of miRNAs targeting the key nuclear receptors regulating CYP3A4 gene expression: The challenge of the CYP3A4 "missing heritability" enigma
2015 |
Faculty of Pharmacy in Hradec Králové
publication
The Aryl Hydrocarbon Receptor in the Human Placental Trophoblast: The Impact of Nutraceuticals and Natural Products
2015 |
Faculty of Pharmacy in Hradec Králové
publication
Nuclear receptors in regulation of biotransformation enzymes and drug transporters in the placental barrier
2014 |
Faculty of Pharmacy in Hradec Králové
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