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doc. PharmDr. Jaroslav Roh Ph.D.
Academic staff at Faculty of Pharmacy in Hradec Králové
8 classes
65 publications
Classes
class
General and Inorganic Chemistry
+2
GAF124 |
Faculty of Pharmacy in Hradec Králové
class
Diploma Thesis I
GAF163 |
Faculty of Pharmacy in Hradec Králové
class
Exercises in General Chemistry
+1
GB208 |
Faculty of Pharmacy in Hradec Králové
class
Diploma Thesis Elaboration I
GF163 |
Faculty of Pharmacy in Hradec Králové
class
Constitution of Organic Compounds
GF224 |
Faculty of Pharmacy in Hradec Králové
Publications
publication
UHPLC-MS/MS method for analysis of sobuzoxane, its active form ICRF-154 and metabolite EDTA-diamide and its application to bioactivation study
2019 |
Faculty of Pharmacy in Hradec Králové
publication
Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-beta-D-ribofuranose 2'-Oxidase
2019 |
Faculty of Pharmacy in Hradec Králové
publication
Pharmacokinetics of the cardioprotective drug dexrazoxane and its active metabolite ADR-925 with focus on cardiomyocytes and the heart
2018 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
2,6-Dihydroxybenzaldehyde analogues of the iron chelator salicylaldehyde isonicotinoyl hydrazone: Increased hydrolytic stability and cytoprotective activity against oxidative stress
2018 |
Faculty of Pharmacy in Hradec Králové
publication
Investigation of novel dexrazoxane analogue JR-311 shows significant cardioprotective effects through topoisomerase IIbeta but not its iron chelating metabolite
2017 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents
2017 |
Faculty of Pharmacy in Hradec Králové
publication
Characterization of cytoprotective and toxic properties of iron chelator SIH, prochelator BSIH and their degradation products
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Synthesis and analysis of novel analogues of dexrazoxane and its open-ring hydrolysis product for protection against anthracycline cardiotoxicity in vitro and in vivo
2015 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead agents
2015 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
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