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force degradation
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doc. PharmDr. Jaroslav Roh Ph.D.
Academic staff at Faculty of Pharmacy in Hradec Králové
8 classes
65 publications
Classes
class
General and Inorganic Chemistry
+2
GAF124 |
Faculty of Pharmacy in Hradec Králové
class
Diploma Thesis I
GAF163 |
Faculty of Pharmacy in Hradec Králové
class
Exercises in General Chemistry
+1
GB208 |
Faculty of Pharmacy in Hradec Králové
class
Diploma Thesis Elaboration I
GF163 |
Faculty of Pharmacy in Hradec Králové
class
Constitution of Organic Compounds
GF224 |
Faculty of Pharmacy in Hradec Králové
Publications
publication
A UHPLC-UV-QTOF study on the stability of carfilzomib, a novel proteasome inhibitor
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Both Nitro Groups Are Essential for High Antitubercular Activity of 3,5-Dinitrobenzylsulfanyl Tetrazoles and 1,3,4-Oxadiazoles through the Deazaflavin-Dependent Nitroreductase Activation Pathway
2024 |
Faculty of Pharmacy in Hradec Králové
publication
Pyrimidine derivatives with antitubercular activity
2023 |
Faculty of Pharmacy in Hradec Králové
publication
2,6-Disubstituted 7-(naphthalen-2-ylmethyl)-7H-purines as a new class of potent antitubercular agents inhibiting DprE1
2023 |
Faculty of Pharmacy in Hradec Králové
publication
The UHPLC-UV method applied for the forced degradation study of ixazomib and HRMS identification of its degradation products
2023 |
Faculty of Pharmacy in Hradec Králové
publication
7-Azaindole, 2,7-diazaindole, and 1H-pyrazole as core structures for novel anticancer agents with potential chemosensitizing properties
2022 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Examination of diverse iron-chelating agents for the protection of differentiated PC12 cells against oxidative injury induced by 6-hydroxydopamine and dopamine
2022 |
Faculty of Pharmacy in Hradec Králové
publication
Proline, hydroxyproline, and pyrrolidone carboxylic acid derivatives as highly efficient but reversible transdermal permeation enhancers
2022 |
Faculty of Pharmacy in Hradec Králové
publication
Structure-Activity Relationship Study of Dexrazoxane Analogues Reveals ICRF-193 as the Most Potent Bisdioxopiperazine against Anthracycline Toxicity to Cardiomyocytes Due to Its Strong Topoisomerase II beta Interactions
2021 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Prodrug of ICRF-193 provides promising protective effects against chronic anthracycline cardiotoxicity in a rabbit model in vivo
2021 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
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