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switch therapy
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MUDr. Tomáš Rozkoš Ph.D.
Academic staff at Faculty of Medicine in Hradec Králové
21 publications
Publications
publication
Tazemetostat synergistically combats multidrug resistance by the unique triple inhibition of ABCB1, ABCC1, and ABCG2 efflux transporters in vitro and ex vivo
2023 |
Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
publication
Sonidegib potentiates the cancer cells' sensitivity to cytostatic agents by functional inhibition of ABCB1 and ABCG2 in vitro and ex vivo
2022 |
Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
publication
Talazoparib Does Not Interact with ABCB1 Transporter or Cytochrome P450s, but Modulates Multidrug Resistance Mediated by ABCC1 and ABCG2: An in Vitro and Ex Vivo Study
2022 |
Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
publication
Encorafenib Acts as a Dual-Activity Chemosensitizer through Its Inhibitory Effect on ABCC1 Transporter In Vitro and Ex Vivo
2022 |
Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
publication
Tepotinib Inhibits Several Drug Efflux Transporters and Biotransformation Enzymes: The Role in Drug-Drug Interactions and Targeting Cytostatic Resistance In Vitro and Ex Vivo
2021 |
Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
publication
The Time Between Chemoradiation and Surgery for Rectal Carcinoma Negatively Influences Mesorectal Excision Quality
2020 |
Faculty of Medicine in Hradec Králové
publication
Predictive diagnostics of gastric cancer in 2018
2018 |
Faculty of Medicine in Hradec Králové, Faculty of Medicine in Pilsen
publication
Identification of an optimal algorithm for effective diagnostics of non-small cell lung cancer with ALK gene rearrangement - implementation of the method and practical experiences with routine diagnostics
2017 |
Faculty of Medicine in Hradec Králové, First Faculty of Medicine
publication
PD-L1 testing - new challenge in predictive diagnostics of non-small cell lung carcinoma
2016 |
Faculty of Medicine in Hradec Králové
publication
EGFR in triple negative breast carcinoma: significance of protein expression and high gene copy number
2015 |
Faculty of Medicine in Hradec Králové
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