Publications
- Early and delayed cardioprotective intervention with dexrazoxane each show different potential for prevention of chronic anthracycline cardiotoxicity in rabbits2013 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Comparison of clinically used and experimental iron chelators for protection against oxidative stress-induced cellular injury2010 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- In vitro and in vivo examination of cardiac troponins as biochemical markers of drug-induced cardiotoxicity +12007 | Faculty of Medicine in Hradec Králové
- Evaluation of ECG time intervals in a rabbit model of anthracycline-induced cardiomyopathy: a useful tool for assessment of cardioprotective agents +12007 | Faculty of Medicine in Hradec Králové
- Troponin as a marker of myocardiac damage in drug-induced cardiotoxicity +12005 | Faculty of Medicine in Hradec Králové
- Primary prevention of chronic anthracycline cardiotoxicity with ACE inhibitor is temporarily effective in rabbits, but benefits wane in post-treatment follow-up2022 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Prodrug of ICRF-193 provides promising protective effects against chronic anthracycline cardiotoxicity in a rabbit model in vivo2021 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Clinically Translatable Prevention of Anthracycline Cardiotoxicity by Dexrazoxane Is Mediated by Topoisomerase II Beta and Not Metal Chelation2021 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Development of water-soluble prodrugs of the bisdioxopiperazine topoisomerase II beta inhibitor ICRF-193 as potential cardioprotective agents against anthracycline cardiotoxicity2021 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
- Investigation of Structure-Activity Relationships of Dexrazoxane Analogs Reveals Topoisomerase II beta Interaction as a Prerequisite for Effective Protection against Anthracycline Cardiotoxicity2020 | Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
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