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Primary human hepatocytes
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prof. PharmDr. Petr Pávek Ph.D.
Academic staff at Faculty of Pharmacy in Hradec Králové
12 classes
194 publications
Classes
class
Personalized Pharmacotherapy and Pharmacogenetics
+1
GAF356 |
Faculty of Pharmacy in Hradec Králové
class
Introduction to Pharmacology and Toxicology
+1
GB174 |
Faculty of Pharmacy in Hradec Králové
class
Pharmacology and Toxicology
+1
GB180 |
Faculty of Pharmacy in Hradec Králové
class
Nutrigenomics
+3
GDEFGN02 |
Faculty of Pharmacy in Hradec Králové
class
Clinical Pharmacokinetics
+1
GDEKSF16 |
Faculty of Pharmacy in Hradec Králové
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Publications
publication
Effects of anthocyanins on the AhR-CYP1A1 signaling pathway in human hepatocytes and human cancer cell lines
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Pelargonidin activates the AhR and induces CYP1A1 in primary human hepatocytes and human cancer cell lines HepG2 and LS174T
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Glucocorticoid receptor regulates organic cation transporter 1 (OCT1, SLC22A1) expression via HNF4alpha upregulation in primary human hepatocytes
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Rifampicin does not significantly affect the expression of small heterodimer partner in primary human hepatocytes
2012 |
Faculty of Pharmacy in Hradec Králové
publication
Investigation of Orlistat effects on PXR activation and CYP3A4 expression in primary human hepatocytes and human intestinal LS174T cells
2010 |
Central Library of Charles University
publication
Benzodiazepines medazepam and midazolam are activators of pregnane X receptor and weak inducers of CYP3A4: Investigation in primary cultures of human hepatocytes and hepatocarcinoma cell lines
2010 |
Central Library of Charles University
publication
Dexamethasone controls aryl hydrocarbon receptor (AhR)-mediated CYP1A1 and CYP1A2 expression and activity in primary cultures of human hepatocytes
2009 |
Central Library of Charles University
publication
JNK inhibitor SP600125 is a partial agonist of human aryl hydrocarbon receptor and induces CYP1A1 and CYP1A2 genes in primary human hepatocytes
2008 |
Central Library of Charles University
publication
Both Nitro Groups Are Essential for High Antitubercular Activity of 3,5-Dinitrobenzylsulfanyl Tetrazoles and 1,3,4-Oxadiazoles through the Deazaflavin-Dependent Nitroreductase Activation Pathway
2024 |
Faculty of Pharmacy in Hradec Králové
publication
Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure
2023 |
Faculty of Pharmacy in Hradec Králové, Central Library of Charles University, First Faculty of Medicine
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