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drugs metabolism
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prof. PharmDr. Petr Pávek Ph.D.
Academic staff at Faculty of Pharmacy in Hradec Králové
12 classes
194 publications
Classes
class
Personalized Pharmacotherapy and Pharmacogenetics
+1
GAF356 |
Faculty of Pharmacy in Hradec Králové
class
Introduction to Pharmacology and Toxicology
+1
GB174 |
Faculty of Pharmacy in Hradec Králové
class
Pharmacology and Toxicology
+1
GB180 |
Faculty of Pharmacy in Hradec Králové
class
Nutrigenomics
+3
GDEFGN02 |
Faculty of Pharmacy in Hradec Králové
class
Clinical Pharmacokinetics
+1
GDEKSF16 |
Faculty of Pharmacy in Hradec Králové
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Publications
publication
The role of residues T248, Y249 and T422 in the function of human pregnane X receptor
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Construction and characterization of peroxisome proliferator-activated receptor-gamma co-activator 1 alpha (PGC-1 alpha over-expressing cell line derived from human hepatocyte carcinoma HepG2 cells)
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Construction and characterization of hepatocyte nuclear factor HNF4alpha1 over-expressing cell line derived from human hepatoma HepG2 cells
2011 |
Faculty of Pharmacy in Hradec Králové
publication
Metabolism of drugs and other xenobiotics
2011 |
Faculty of Pharmacy in Hradec Králové
publication
Regulation of drug-metabolizing cytochrome P450 enzymes by glucocorticoids
2010 |
Central Library of Charles University
publication
Investigation of Orlistat effects on PXR activation and CYP3A4 expression in primary human hepatocytes and human intestinal LS174T cells
2010 |
Central Library of Charles University
publication
Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug-metabolizing cytochrome P450 enzymes
2010 |
Faculty of Pharmacy in Hradec Králové
publication
Dexamethasone controls aryl hydrocarbon receptor (AhR)-mediated CYP1A1 and CYP1A2 expression and activity in primary cultures of human hepatocytes
2009 |
Central Library of Charles University
publication
Both Nitro Groups Are Essential for High Antitubercular Activity of 3,5-Dinitrobenzylsulfanyl Tetrazoles and 1,3,4-Oxadiazoles through the Deazaflavin-Dependent Nitroreductase Activation Pathway
2024 |
Faculty of Pharmacy in Hradec Králové
publication
Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure
2023 |
Faculty of Pharmacy in Hradec Králové, Central Library of Charles University, First Faculty of Medicine
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