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Multi-target directed ligands
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doc. RNDr. Radim Havelek Ph.D.
Academic staff at Faculty of Medicine in Hradec Králové
4 classes
62 publications
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Cellular Pathobiochemistry
+3
FG50036 |
Faculty of Medicine in Hradec Králové
Publications
publication
Derivatives of the beta-Crinane Amaryllidaceae Alkaloid Haemanthamine as Multi-Target Directed Ligands for Alzheimer's Disease
2019 |
Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
publication
Flubendazole exhibits anti-glioblastoma effect by inhibiting STAT3 and promoting cell cycle arrest
2023 |
Faculty of Medicine in Hradec Králové, First Faculty of Medicine
publication
Antiproliferative activity and apoptosis-inducing mechanism of Amaryllidaceae alkaloid montanine on A549 and MOLT-4 human cancer cells
2023 |
Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
publication
Design of semisynthetic derivatives of the Amaryllidaceae alkaloid ambelline and exploration of their in vitro cytotoxic activities
2023 |
Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
publication
Rh(III) and Ru(II) complexes with phosphanyl-alkylamines: inhibition of DNA synthesis induced by anticancer Rh complex
2023 |
Faculty of Medicine in Hradec Králové
publication
Multimodal Contrast Agent Enabling pH Sensing Based on Organically Functionalized Gold Nanoshells with Mn-Zn Ferrite Cores
2022 |
Faculty of Medicine in Hradec Králové, First Faculty of Medicine, Faculty of Mathematics and Physics
publication
7-Azaindole, 2,7-diazaindole, and 1H-pyrazole as core structures for novel anticancer agents with potential chemosensitizing properties
2022 |
Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
publication
Semisynthetic derivatives of haemanthamine and their in vitro antiproliferative activity evaluation against a panel of human cell lines
2022 |
Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
publication
Monoclonal anti-endoglin antibody TRC105 (carotuximab) prevents hypercholesterolemia and hyperglycemia-induced endothelial dysfunction in human aortic endothelial cells
2022 |
Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
publication
The Effect of Chronic Exposure of Graphene Nanoplates on the Viability and Motility of A549 Cells
2022 |
Faculty of Medicine in Hradec Králové
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