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prof. MUDr. Pavel Klener Ph.D.
Academic staff at First Faculty of Medicine
112 publications
Publications
publication
Downregulation of deoxycytidine kinase in cytarabine-resistant mantle cell lymphoma cells confers cross-resistance to nucleoside analogs gemcitabine, fludarabine and cladribine, but not to other classes of anti-lymphoma agents
2014 |
First Faculty of Medicine
publication
Multi-level disruption of the extrinsic apoptotic pathway mediates resistance of leukemia cells to TNF-related apoptosis-inducing ligand (TRAIL)
2013 |
First Faculty of Medicine
publication
Resistance to TRAIL in mantle cell lymphoma cells is associated with the decreased expression of purine metabolism enzymes
2013 |
First Faculty of Medicine
publication
Principles of systemic anticancer treatment
2013 |
First Faculty of Medicine
publication
Update on the molecular pathogenesis and clinical treatment of mantle cell lymphoma: report of the 11th annual conference of the European Mantle Cell Lymphoma Network
2013 |
First Faculty of Medicine
publication
Basic principles of the treatment of hematological malignancies
2013 |
First Faculty of Medicine
publication
TRAIL-induced apoptosis of HL60 leukemia cells: two distinct phenotypes of acquired TRAIL resistance that are accompanied with resistance to TNF alpha but not to idarubicin and cytarabine
2009 |
First Faculty of Medicine
publication
Cell Death Signalling Pathways in the Pathogenesis and Therapy of Haematologic Malignancies: Overview of Therapeutic Approaches
2006 |
First Faculty of Medicine
publication
Cell Death Signalling Pathways in the Pathogenesis and Therapy of Haematologic Maliggnancies: Overview of Apoptotic Patways
2006 |
First Faculty of Medicine
publication
Ibrutinib in mantle cell lymphoma: a real-world retrospective multi-center analysis of 77 patients treated in the Czech Republic
2023 |
First Faculty of Medicine, Faculty of Medicine in Hradec Králové, Third Faculty of Medicine
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