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prof. MUDr. Pavel Klener Ph.D.
Academic staff at First Faculty of Medicine
112 publications
Publications
publication
Targeting of BCL2 Family Proteins with ABT-199 and Homoharringtonine Reveals BCL2-and MCL1-Dependent Subgroups of Diffuse Large B-Cell Lymphoma
2016 |
First Faculty of Medicine, Second Faculty of Medicine
publication
Lenalidomide enhances antitumor functions of chimeric antigen receptor modified T cells
2016 |
First Faculty of Medicine
publication
Detailed Functional and Proteomic Characterization of Fludarabine Resistance in Mantle Cell Lymphoma Cells
2015 |
First Faculty of Medicine
publication
Mouse models of mantle cell lymphoma, complex changes in gene expression and phenotype of engrafted MCL cells: implications for preclinical research
2014 |
First Faculty of Medicine, Faculty of Medicine in Hradec Králové
publication
Downregulation of deoxycytidine kinase in cytarabine-resistant mantle cell lymphoma cells confers cross-resistance to nucleoside analogs gemcitabine, fludarabine and cladribine, but not to other classes of anti-lymphoma agents
2014 |
First Faculty of Medicine
publication
Roscovitine sensitizes leukemia and lymphoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis
2013 |
Central Library of Charles University, First Faculty of Medicine
publication
The plant alkaloid and anti-leukemia drug homoharringtonine sensitizes resistant human colorectal carcinoma cells to TRAIL-induced apoptosis via multiple mechanisms
2013 |
Central Library of Charles University, First Faculty of Medicine
publication
Multi-level disruption of the extrinsic apoptotic pathway mediates resistance of leukemia cells to TNF-related apoptosis-inducing ligand (TRAIL)
2013 |
First Faculty of Medicine
publication
ABL1, SRC and other non-receptor tyrosine-kinases as new targets for specific anticancer therapy
2010 |
First Faculty of Medicine
publication
The cultivation of human multipotent mesenchymal stromal cells in clinical grade medium for bone tissue engineering
2009 |
First Faculty of Medicine, Second Faculty of Medicine, Faculty of Medicine in Hradec Králové
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