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prof. MUDr. Pavel Klener Ph.D.
Academic staff at First Faculty of Medicine
112 publications
Publications
publication
Lenalidomide enhances antitumor functions of chimeric antigen receptor modified T cells
2016 |
First Faculty of Medicine
publication
Pevonedistat, a NEDD8-activating enzyme inhibitor, is active in mantle cell lymphoma and enhances rituximab activity in vivo
2016 |
First Faculty of Medicine
publication
Mouse models of mantle cell lymphoma, complex changes in gene expression and phenotype of engrafted MCL cells: implications for preclinical research
2014 |
First Faculty of Medicine, Faculty of Medicine in Hradec Králové
publication
Downregulation of deoxycytidine kinase in cytarabine-resistant mantle cell lymphoma cells confers cross-resistance to nucleoside analogs gemcitabine, fludarabine and cladribine, but not to other classes of anti-lymphoma agents
2014 |
First Faculty of Medicine
publication
In Vivo Growth of Mantle Cell Lymphoma Xenografts in Immunodeficient Mice Is Positively Regulated by VEGF and Associated with Significant Up-regulation of CD31/PECAM1
2013 |
First Faculty of Medicine, Faculty of Medicine in Hradec Králové
publication
Ibrutinib in mantle cell lymphoma: a real-world retrospective multi-center analysis of 77 patients treated in the Czech Republic
2023 |
First Faculty of Medicine, Faculty of Medicine in Hradec Králové, Third Faculty of Medicine
publication
mTOR inhibition amplifies the anti-lymphoma effect of PI3Kβ/δ blockage in diffuse large B-cell lymphoma
2023 |
First Faculty of Medicine, Third Faculty of Medicine
publication
Sequencing-based analysis of clonal evolution of 25 mantle cell lymphoma patients at diagnosis and after failure of standard immunochemotherapy
2023 |
First Faculty of Medicine, Second Faculty of Medicine
publication
Cell-specific modulation of mitochondrial respiration and metabolism by the pro-apoptotic Bcl-2 family members Bax and Bak
2023 |
First Faculty of Medicine, Faculty of Science
publication
Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2-b]pyridazine Derivatives Identified by Scaffold Hopping
2023 |
First Faculty of Medicine
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