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xenograft
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prof. MUDr. Pavel Klener Ph.D.
Academic staff at First Faculty of Medicine
112 publications
Publications
publication
Targeting of BCL2 Family Proteins with ABT-199 and Homoharringtonine Reveals BCL2-and MCL1-Dependent Subgroups of Diffuse Large B-Cell Lymphoma
2016 |
First Faculty of Medicine, Second Faculty of Medicine
publication
Single-agent cytarabine is insufficient for the treatment of human mantle cell lymphoma in mouse xenograft model
2016 |
First Faculty of Medicine, Faculty of Medicine in Hradec Králové
publication
Anti-Lymphoma Efficacy Comparison of Anti-CD20 Monoclonal Antibody-Targeted and Non-Targeted Star-Shaped Polymer-Prodrug Conjugates
2015 |
First Faculty of Medicine
publication
Mouse models of mantle cell lymphoma, complex changes in gene expression and phenotype of engrafted MCL cells: implications for preclinical research
2014 |
First Faculty of Medicine, Faculty of Medicine in Hradec Králové
publication
Downregulation of deoxycytidine kinase in cytarabine-resistant mantle cell lymphoma cells confers cross-resistance to nucleoside analogs gemcitabine, fludarabine and cladribine, but not to other classes of anti-lymphoma agents
2014 |
First Faculty of Medicine
publication
In Vivo Growth of Mantle Cell Lymphoma Xenografts in Immunodeficient Mice Is Positively Regulated by VEGF and Associated with Significant Up-regulation of CD31/PECAM1
2013 |
First Faculty of Medicine, Faculty of Medicine in Hradec Králové
publication
Ibrutinib in mantle cell lymphoma: a real-world retrospective multi-center analysis of 77 patients treated in the Czech Republic
2023 |
First Faculty of Medicine, Faculty of Medicine in Hradec Králové, Third Faculty of Medicine
publication
mTOR inhibition amplifies the anti-lymphoma effect of PI3Kβ/δ blockage in diffuse large B-cell lymphoma
2023 |
First Faculty of Medicine, Third Faculty of Medicine
publication
Sequencing-based analysis of clonal evolution of 25 mantle cell lymphoma patients at diagnosis and after failure of standard immunochemotherapy
2023 |
First Faculty of Medicine, Second Faculty of Medicine
publication
Cell-specific modulation of mitochondrial respiration and metabolism by the pro-apoptotic Bcl-2 family members Bax and Bak
2023 |
First Faculty of Medicine, Faculty of Science
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