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AChE-Is
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prof. Ing. Kamil Kuča Ph.D.
Academic staff at Faculty of Medicine in Hradec Králové
380 publications
Publications
publication
7-MEOTA-donepezil like compounds as cholinesterase inhibitors: Synthesis, pharmacological evaluation, molecular modeling and QSAR studies
2014 |
Faculty of Pharmacy in Hradec Králové, Faculty of Science
publication
Entry of oxime K027 into the different parts of rat brain: Comparison with obidoxime and oxime HI-6
2014 |
Publication without faculty affiliation
publication
Prophylactic administration of non-organophosphate cholinesterase inhibitors before acute exposure to organophosphates: assessment using terbufos sulfone
2014 |
Publication without faculty affiliation
publication
Impact of paraoxon followed by acetylcholinesterase reactivator HI-6 on gastric myoelectric activity in experimental pigs
2013 |
Faculty of Medicine in Hradec Králové
publication
The summary on non-reactivation cholinergic properties of oxime reactivators: the interaction with muscarinic and nicotinic receptors
2013 |
Publication without faculty affiliation
publication
Oximes: Inhibitors of Human Recombinant Acetylcholinesterase. A Structure-Activity Relationship (SAR) Study
+1
2013 |
Publication without faculty affiliation
publication
Acetylcholinesterase reactivators (HI-6, obidoxime, trimedoxime, K027, K075, K127, K203, K282): structural evaluation of human serum albumin binding and absorption Kinetics
2013 |
Publication without faculty affiliation
publication
The preparation, in vitro screening and molecular docking of symmetrical bisquaternary cholinesterase inhibitors containing a but-(2E)-en-1,4-diyl connecting linkage
2011 |
Faculty of Pharmacy in Hradec Králové
publication
Effects of K074 and pralidoxime on antioxidant and acetylcholinesterase response in malathion-poisoned mice
2011 |
Publication without faculty affiliation
publication
The measured CSF/plasma donepezil concentration ratio but not individually measured CSF and plasma concentrations significantly increase over 24 h after donepezil treatment in patients with Alzheimer's disease
2023 |
Faculty of Medicine in Hradec Králové, Second Faculty of Medicine
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