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Crystal structure
Person
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Mgr. Dominika Chalupská Ph.D.
External person at Central Library of Charles University
12 publications
Publications
publication
Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold
2022 |
Central Library of Charles University, Faculty of Science
publication
Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein
2020 |
Central Library of Charles University, Faculty of Science
publication
Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein
2016 |
Central Library of Charles University, Faculty of Science
publication
The high-resolution crystal structure of phosphatidylinositol 4-kinase IIβ and the crystal structure of phosphatidylinositol 4-kinase IIα containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design
2015 |
Central Library of Charles University
publication
The crystal structure of the phosphatidylinositol 4-kinase IIα
2014 |
Central Library of Charles University
publication
The pathogenic N650K variant in the GluN1 subunit regulates the trafficking, conductance, and pharmacological properties of NMDA receptors
2023 |
Central Library of Charles University, Faculty of Science
publication
Rational Design of Highly Potent SARS-CoV-2 nsp14 Methyltransferase Inhibitors
2023 |
Central Library of Charles University, Faculty of Science
publication
Subunit-Dependent Surface Mobility and Localization of NMDA Receptors in Hippocampal Neurons Measured Using Nanobody Probes
2023 |
Central Library of Charles University, Faculty of Science
publication
Exploring positions 6 and 7 of a quinazoline-based scaffold leads to changes in selectivity and potency towards RIPK2/3 kinases
2023 |
Central Library of Charles University, Faculty of Science
publication
Localization of SARS-CoV-2 Capping Enzymes Revealed by an Antibody against the nsp10 Subunit
2021 |
Central Library of Charles University
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