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molecular modelling
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doc. PharmDr. Ondřej Soukup Ph.D.
External academic staff at Faculty of Pharmacy in Hradec Králové
189 publications
Publications
publication
Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation
2017 |
Publication without faculty affiliation
publication
Tetrahydropyranodiquinolin-8-amines as new, non hepatotoxic, antioxidant, and acetylcholinesterase inhibitors for Alzheimer's disease therapy
2017 |
Publication without faculty affiliation
publication
Synthesis, antimicrobial evaluation and molecular modeling of 5-hydroxyisoquinolinium salt series; the effect of the hydroxyl moiety
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Towards understanding the mechanism of action of antibacterial N-alkyl-3-hydroxypyridinium salts: Biological activities, molecular modeling and QSAR studies
2016 |
Publication without faculty affiliation
publication
Tacrine-Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity
2015 |
Publication without faculty affiliation
publication
7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment
2015 |
Publication without faculty affiliation
publication
7-Methoxytacrine-Adamantylamine Heterodimers as Cholinesterase Inhibitors in Alzheimer's Disease Treatment - Synthesis, Biological Evaluation and Molecular Modeling Studies
2013 |
Publication without faculty affiliation
publication
Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition
2024 |
Faculty of Science, First Faculty of Medicine, Third Faculty of Medicine
publication
Nakagami imaging and morphing for multiple sclerosis lesion volume estimation
2024 |
Publication without faculty affiliation
publication
Differentiated SH-SY5Y neuroblastoma cells as a model for evaluation of nerve agent-associated neurotoxicity
2023 |
Faculty of Pharmacy in Hradec Králové, First Faculty of Medicine
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