Publications
- U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells2014 | Faculty of Pharmacy in Hradec Králové
- Valproate activates ERK signaling pathway in primary human hepatocytes2014 | Faculty of Pharmacy in Hradec Králové
- Rifampicin does not significantly affect the expression of small heterodimer partner in primary human hepatocytes2012 | Faculty of Pharmacy in Hradec Králové
- Valproic acid augments vitamin D receptor-mediated induction of CYP24 by vitamin D3: a possible cause of valproic acid-induced osteomalacia?2011 | Faculty of Pharmacy in Hradec Králové
- Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug-metabolizing cytochrome P450 enzymes2010 | Faculty of Pharmacy in Hradec Králové
- Evidence of cross-talk between aryl hydrocarbon receptor and glucocorticoid receptor in placental trophoblast JEG3 cellsPublication without faculty affiliation
- Pharmacogenetics of nuclear receptor in CYP3A4 gene regulationPublication without faculty affiliation
- Role of extracellular-signal regulated kinase (ERK) pathway in PXR-mediated valproic acid-induced activation of CYP3A4 expressionPublication without faculty affiliation
- Valproic acid induces CYP3A4 expression through Pregnane X (PXR) and Constitutive androstane (CAR) nuclear receptor pathwaysPublication without faculty affiliation
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