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drug-resistance
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doc. Mgr. Kateřina Machová Poláková Ph.D.
Academic staff at First Faculty of Medicine
13 publications
Publications
publication
Exosomes released by imatinib-resistant K562 cells contain specific membrane markers, IFITM3, CD146 and CD36 and increase the survival of imatinib-sensitive cells in the presence of imatinib
2021 |
First Faculty of Medicine, Faculty of Science, Central Library of Charles University
publication
BCR-ABL1 mediated miR-150 downregulation through MYC contributed to myeloid differentiation block and drug resistance in chronic myeloid leukemia.
2018 |
First Faculty of Medicine, Central Library of Charles University
publication
BCR-ABL1 mediated miR-150 downregulation through MYC contributed to myeloid differentiation block and drug resistance in chronic myeloid leukemia
2018 |
First Faculty of Medicine, Central Library of Charles University
publication
Proteomic analysis of imatinib-resistant CML-T1 cells reveals calcium homeostasis as a potential therapeutic target
2016 |
First Faculty of Medicine, Faculty of Science
publication
Somatic Mutations in Oncogenes Are in Chronic Myeloid Leukemia Acquired De Novo via Deregulated Base-Excision Repair and Alternative Non-Homologous End Joining
2021 |
First Faculty of Medicine, Second Faculty of Medicine, Faculty of Physical Education and Sport
publication
Sensitivity and reliability of DNA-based mutation analysis by allele-specific digital PCR to follow resistant BCR-ABL1-positive cells
2021 |
First Faculty of Medicine
publication
Analysis of chronic myeloid leukaemia during deep molecular response by genomic PCR: a traffic light stratification model with impact on treatment-free remission
2020 |
First Faculty of Medicine, Second Faculty of Medicine
publication
Genotypes of SLC22A4 and SLC22A5 regulatory loci are predictive of the response of chronic myeloid leukemia patients to imatinib treatment
2017 |
First Faculty of Medicine, Faculty of Science, Faculty of Medicine in Hradec Králové
publication
Interferon-alpha Revisited: Individualized Treatment Management Eased the Selective Pressure of Tyrosine Kinase Inhibitors on BCR-ABL1 Mutations Resulting in a Molecular Response in High-Risk CML Patients
2016 |
First Faculty of Medicine, Faculty of Science, Third Faculty of Medicine
publication
Characterization of 46 patient-specific BCR-ABL1 fusions and detection of SNPs upstream and downstream the breakpoints in chronic myeloid leukemia using next generation sequencing
2015 |
First Faculty of Medicine, Second Faculty of Medicine
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