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Anthracyclines
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prof. PharmDr. Tomáš Šimůnek Ph.D.
Academic staff at Faculty of Pharmacy in Hradec Králové
15 classes
162 publications
Classes
class
Molecular Biology
+6
GAF144 |
Faculty of Pharmacy in Hradec Králové
class
Molecular Biology and Genetics
+5
GAF370 |
Faculty of Pharmacy in Hradec Králové
class
Molecular Basis of Pharmacology and Toxicology
+1
GDEFX05 |
Faculty of Pharmacy in Hradec Králové
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Publications
publication
Oxidative Stress, Redox Signaling, and Metal Chelation in Anthracycline Cardiotoxicity and Pharmacological Cardioprotection
2013 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Early and delayed cardioprotective intervention with dexrazoxane each show different potential for prevention of chronic anthracycline cardiotoxicity in rabbits
2013 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Catalytic Inhibitors of Topoisomerase II Differently Modulate the Toxicity of Anthracyclines in Cardiac and Cancer Cells
2013 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Development of LC-MS/MS method for the simultaneous analysis of the cardioprotective drug dexrazoxane and its metabolite ADR-925 in isolated cardiomyocytes and cell culture medium
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Chronic anthracycline cardiotoxicity: molecular and functional analysis with focus on nuclear factor erythroid 2-related factor 2 and mitochondrial biogenesis pathways
2012 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
In vivo and in vitro assessment of the role of glutathione antioxidant system in anthracycline-induced cardiotoxicity
2011 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Proteomic insights into chronic anthracycline cardiotoxicity
2011 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron
2009 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Dexrazoxane-afforded protection against chronic anthracycline cardiotoxicity in vivo: effective rescue of cardiomyocytes from apoptotic cell death
2009 |
Central Library of Charles University
publication
Anthracycline toxicity to cardiomyocytes or cancer cells is differently affected by iron chelation with salicylaldehyde isonicotinoyl hydrazone
2008 |
Central Library of Charles University
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