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Multi-targeting
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doc. PharmDr. Jan Korábečný Ph.D.
External academic staff at Faculty of Pharmacy in Hradec Králové
179 publications
Publications
publication
Multi-target-directed therapeutic potential of 7-methoxytacrine-adamantylamine heterodimers in the Alzheimer's disease treatment
2017 |
Publication without faculty affiliation
publication
Multitarget tacrine hybrids with neuroprotective properties to confront Alzheimer's disease
2017 |
Publication without faculty affiliation
publication
The pharmacology of tacrine at N-methyl-D-aspartate receptors
2017 |
Publication without faculty affiliation
publication
Tacrine-Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity
2015 |
Publication without faculty affiliation
publication
7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment
2015 |
Publication without faculty affiliation
publication
7-Methoxytacrine-Adamantylamine Heterodimers as Cholinesterase Inhibitors in Alzheimer's Disease Treatment - Synthesis, Biological Evaluation and Molecular Modeling Studies
2013 |
Publication without faculty affiliation
publication
Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition
2024 |
First Faculty of Medicine, Faculty of Science, Third Faculty of Medicine
publication
In silico library screening to find novel anticancer agent with chemosensitizing properties: focus on targeting ataxia telangiectasia and Rad3 related kinase
2024 |
Faculty of Medicine in Hradec Králové
publication
Differentiated SH-SY5Y neuroblastoma cells as a model for evaluation of nerve agent-associated neurotoxicity
2023 |
First Faculty of Medicine, Faculty of Pharmacy in Hradec Králové
publication
Structure-Guided Design of N-Methylpropargylamino- Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease
2023 |
Faculty of Pharmacy in Hradec Králové, Faculty of Science
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