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léčiva
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RNDr. Věra Černá Ph.D.
Academic staff at Faculty of Science
2 classes
24 publications
Classes
class
Xenobiochemistry
MC250P24 |
Faculty of Science
class
Management of biochemistry
MC250P50 |
Faculty of Science
Publications
publication
Role of cytochromes P450 and peroxidases in metabolism of the anticancer drug ellipticine: additional evidence of their contribution to ellipticine activation in rat liver, lung and kidney
2010 |
Faculty of Science
publication
Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: Studies with the hepatic NADPH: Cytochrome P450 reductase null mouse
+1
2008 |
Faculty of Science
publication
The anticancer drug ellipticine is a potent inducer of rat cytochromes P450 1A1 and 1A2, thereby modulating its own metabolism
2007 |
Faculty of Science
publication
Cytochromes P450 reconstituted with NADPH:P450 reductase mimic the activating and detoxicating metabolism of the anticancer drug ellipticine in microsomes
2006 |
Faculty of Science
publication
Oxidation pattern of the anticancer drug ellipticine by hepatic microsomes - Similarity between human and rat systems
2006 |
Faculty of Science
publication
The study of activation and detoxication metabolism of the anticancer drug ellipticine by cytochromes P450 system in vitro and in vivo
Publication without faculty affiliation
publication
Benzo[a]pyrene-Induced Genotoxicity in Rats Is Affected by Co-Exposure to Sudan I by Altering the Expression of Biotransformation Enzymes
2021 |
Faculty of Science
publication
Chicken immunoglobulins for prophylaxis: Effect of inhaled antibodies on inflammatory parameters in rat airways
2015 |
Faculty of Science, Third Faculty of Medicine
publication
Photo-initiated crosslinking extends mapping of the protein-protein interface to membrane-embedded portions of cytochromes P450 2B4 and b5
2015 |
Faculty of Science
publication
The Anticancer Drug Ellipticine Activated with Cytochrome P450 Mediates DNA Damage Determining Its Pharmacological Efficiencies: Studies with Rats, Hepatic Cytochrome P450 Reductase Null (HRN (TM)) Mice and Pure Enzymes
2015 |
Faculty of Science
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