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In silico
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RNDr. Jana Janočková Ph.D.
External academic staff at Faculty of Medicine in Hradec Králové
37 publications
Publications
publication
Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile
2020 |
Publication without faculty affiliation
publication
From orexin receptor agonist YNT-185 to novel antagonists with drug-like properties for the treatment of insomnia
2020 |
Publication without faculty affiliation
publication
In vitro and in silico Evaluation of Non-Quaternary Reactivators of AChE as Antidotes of Organophosphorus Poisoning - a New Hope or a Blind Alley?
2018 |
Faculty of Pharmacy in Hradec Králové
publication
Rational design of novel TLR4 ligands by in silico screening and their functional and structural characterization in vitro
2018 |
Publication without faculty affiliation
publication
Investigation of new orexin 2 receptor modulators using in silico and in vitro methods
2018 |
Publication without faculty affiliation
publication
Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities
2022 |
Faculty of Medicine in Hradec Králové
publication
Discovery of Dual A beta/Tau Inhibitors and Evaluation of Their Therapeutic Effect on a Drosophila Model of Alzheimer's Disease
2022 |
Publication without faculty affiliation
publication
Tacrine - Benzothiazoles: Novel class of potential multitarget anti-Alzheimer's drugs dealing with cholinergic, amyloid and mitochondrial systems
2021 |
Faculty of Medicine in Hradec Králové, Central Library of Charles University
publication
Huprine Y-Tryptophan heterodimers with potential implication to Alzheimer's disease treatment
2021 |
Faculty of Pharmacy in Hradec Králové, First Faculty of Medicine
publication
2-Propargylamino-naphthoquinone derivatives as multipotent agents for the treatment of Alzheimer's disease
2021 |
Publication without faculty affiliation
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