Publications
- Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities2022 | Faculty of Medicine in Hradec Králové
- Huprine Y-Tryptophan heterodimers with potential implication to Alzheimer's disease treatment2021 | Faculty of Pharmacy in Hradec Králové, First Faculty of Medicine
- Synthesis of New Biscoumarin Derivatives, In Vitro Cholinesterase Inhibition, Molecular Modelling and Antiproliferative Effect in A549 Human Lung Carcinoma Cells2021 | Publication without faculty affiliation
- Design and synthesis of novel tacrine-indole hybrids as potential multitarget-directed ligands for the treatment of Alzheimer's disease2021 | Publication without faculty affiliation
- (+/-)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3 beta Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease2021 | Publication without faculty affiliation
- Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile2020 | Publication without faculty affiliation
- Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase2019 | Publication without faculty affiliation
- Search for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives2019 | Publication without faculty affiliation
- In vitro and in silico Evaluation of Non-Quaternary Reactivators of AChE as Antidotes of Organophosphorus Poisoning - a New Hope or a Blind Alley?2018 | Faculty of Pharmacy in Hradec Králové
- Profiling donepezil template into multipotent hybrids with antioxidant properties2018 | Publication without faculty affiliation
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