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RNDr. Jana Janočková Ph.D.
External academic staff at Faculty of Medicine in Hradec Králové
37 publications
Publications
publication
(+/-)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3 beta Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease
2021 |
Publication without faculty affiliation
publication
Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer's disease therapy
2019 |
Publication without faculty affiliation
publication
Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase
2019 |
Publication without faculty affiliation
publication
Profiling donepezil template into multipotent hybrids with antioxidant properties
2018 |
Publication without faculty affiliation
publication
The antioxidant additive approach for Alzheimer's disease therapy: New ferulic (Lipoic) acid plus melatonin modified tacrines as Cholinesterases inhibitors, direct antioxidants, and nuclear factor (Erythroid-Derived 2)-like 2 activators
2016 |
Publication without faculty affiliation
publication
Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities
2022 |
Faculty of Medicine in Hradec Králové
publication
Discovery of Dual A beta/Tau Inhibitors and Evaluation of Their Therapeutic Effect on a Drosophila Model of Alzheimer's Disease
2022 |
Publication without faculty affiliation
publication
Tacrine - Benzothiazoles: Novel class of potential multitarget anti-Alzheimer's drugs dealing with cholinergic, amyloid and mitochondrial systems
2021 |
Faculty of Medicine in Hradec Králové, Central Library of Charles University
publication
Huprine Y-Tryptophan heterodimers with potential implication to Alzheimer's disease treatment
2021 |
Faculty of Pharmacy in Hradec Králové, First Faculty of Medicine
publication
2-Propargylamino-naphthoquinone derivatives as multipotent agents for the treatment of Alzheimer's disease
2021 |
Publication without faculty affiliation
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