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RNDr. Jana Janočková Ph.D.
Externí akademický pracovník na Lékařská fakulta v Hradci Králové
37 publikací
Publikace
publication
Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities
2022 |
Lékařská fakulta v Hradci Králové
publication
Tacrine - Benzothiazoles: Novel class of potential multitarget anti-Alzheimer's drugs dealing with cholinergic, amyloid and mitochondrial systems
2021 |
Lékařská fakulta v Hradci Králové, Ústřední knihovna
publication
Synthesis of New Biscoumarin Derivatives, In Vitro Cholinesterase Inhibition, Molecular Modelling and Antiproliferative Effect in A549 Human Lung Carcinoma Cells
2021 |
Publikace bez příslušnosti k fakultě
publication
Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile
2020 |
Publikace bez příslušnosti k fakultě
publication
N-alkylated tacrine derivatives as potential agents in Alzheimer's disease therapy
2019 |
Lékařská fakulta v Hradci Králové
publication
Search for multifunctional agents against Alzheimer's disease among non-imidazole histamine H3 receptor ligands. In vitro and in vivo pharmacological evaluation and computational studies of piperazine derivatives
2019 |
Publikace bez příslušnosti k fakultě
publication
In vitro and in silico Evaluation of Non-Quaternary Reactivators of AChE as Antidotes of Organophosphorus Poisoning - a New Hope or a Blind Alley?
2018 |
Farmaceutická fakulta v Hradci Králové
publication
Tacrine-coumarin and Tacrine-7-chloroquinoline Hybrids with Thiourea Linkers: Cholinesterase Inhibition Properties, Kinetic Study, Molecular Docking and Permeability Assay for Blood-brain Barrier
2018 |
Publikace bez příslušnosti k fakultě
publication
Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation
2017 |
Publikace bez příslušnosti k fakultě
publication
The antioxidant additive approach for Alzheimer's disease therapy: New ferulic (Lipoic) acid plus melatonin modified tacrines as Cholinesterases inhibitors, direct antioxidants, and nuclear factor (Erythroid-Derived 2)-like 2 activators
2016 |
Publikace bez příslušnosti k fakultě
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