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Mgr. et Mgr. Evžen Bouřa Ph.D.
External academic staff at Central Library of Charles University
47 publications
Publications
publication
Exploring positions 6 and 7 of a quinazoline-based scaffold leads to changes in selectivity and potency towards RIPK2/3 kinases
2023 |
Faculty of Science, Central Library of Charles University
publication
Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists
2022 |
Faculty of Science, Central Library of Charles University, Faculty of Physical Education and Sport
publication
Discovery of isonucleotidic CDNs as potent STING agonists with immunomodulatory potential
2022 |
Faculty of Science, Central Library of Charles University
publication
Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold
2022 |
Faculty of Science, Central Library of Charles University
publication
Model of abasic site DNA cross-link repair; from the architecture of NEIL3 DNA binding domains to the X-structure model
2022 |
Faculty of Science, Central Library of Charles University
publication
Protein-Ligand Interactions in the STING Binding Site Probed by Rationally Designed Single-Point Mutations: Experiment and Theory
2021 |
Faculty of Science, Central Library of Charles University
publication
Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses
2021 |
Faculty of Science, Central Library of Charles University
publication
Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3',3'-c-di(2'F,2'dAMP)
2021 |
Faculty of Science, Central Library of Charles University
publication
Enzymatic Synthesis of 3'-5', 3'-5' Cyclic Dinucleotides, Their Binding Properties to the Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations
2021 |
Faculty of Science, Central Library of Charles University
publication
Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein
2021 |
Central Library of Charles University
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