Study programme
Classes
- General Biochemistry +1GAF141 | Faculty of Pharmacy in Hradec Králové
- Xenobiochemistry +1GAF237 | Faculty of Pharmacy in Hradec Králové
- Xenobiochemistry - Practical Training +3GAF267 | Faculty of Pharmacy in Hradec Králové
- Selected Chapters from General Biochemistry +1GDEXP04 | Faculty of Pharmacy in Hradec Králové
- The Defense of Doctoral Thesis +1GDEXPODP1 | Faculty of Pharmacy in Hradec Králové
- Xenobiochemistry and Patobiochemistry +1GDEXPSDZ1 | Faculty of Pharmacy in Hradec Králové
Publications
- Role of carbonyl reducing enzymes in the phase I biotransformation of the non-steroidal anti-inflammatory drug nabumetone in vitro2013 | Faculty of Pharmacy in Hradec Králové
- Efficient isolation of carbonyl-reducing enzymes using affinity approach with anticancer drug oracin as a specific ligand2013 | Faculty of Pharmacy in Hradec Králové
- S-Nitrosoglutathione covalently modifies cysteine residues of human carbonyl reductase 1 and affects its activity2013 | Faculty of Pharmacy in Hradec Králové
- Studies on reduction of S-nitrosoglutathione by human carbonyl reductases 1 and 32011 | Faculty of Pharmacy in Hradec Králové
- Human carbonyl reductases2010 | Central Library of Charles University
- Structural basis for substrate specificity in human monomeric carbonyl reductases2009 | Central Library of Charles University
- Bruton's Tyrosine Kinase Inhibitor Zanubrutinib Effectively Modulates Cancer Resistance by Inhibiting Anthracycline Metabolism and Efflux2022 | Faculty of Pharmacy in Hradec Králové
- Isocitrate dehydrogenase 2 inhibitor enasidenib synergizes daunorubicin cytotoxicity by targeting aldo-keto reductase 1C3 and ATP-binding cassette transporters2022 | Faculty of Pharmacy in Hradec Králové
- Inhibition of AKR1B10-mediated metabolism of daunorubicin as a novel off-target effect for the Bcr-Abl tyrosine kinase inhibitor dasatinib2021 | Faculty of Pharmacy in Hradec Králové
- Selective inhibition of aldo-keto reductase 1C3: a novel mechanism involved in midostaurin and daunorubicin synergism2021 | Faculty of Pharmacy in Hradec Králové
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