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Drug resistance
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prof. Ing. Vladimír Wsól Ph.D.
Academic staff at Faculty of Pharmacy in Hradec Králové
2 study programmes
14 classes
198 publications
Study programme
programme
Xenobiochemistry and Pathobiochemistry
+1
🇨🇿 PhD. |
Faculty of Pharmacy in Hradec Králové
Classes
class
General Biochemistry
+1
GAF141 |
Faculty of Pharmacy in Hradec Králové
class
Xenobiochemistry
+1
GAF237 |
Faculty of Pharmacy in Hradec Králové
class
Xenobiochemistry - Practical Training
+3
GAF267 |
Faculty of Pharmacy in Hradec Králové
class
Selected Chapters from General Biochemistry
+1
GDEXP04 |
Faculty of Pharmacy in Hradec Králové
class
The Defense of Doctoral Thesis
+1
GDEXPODP1 |
Faculty of Pharmacy in Hradec Králové
class
Xenobiochemistry and Patobiochemistry
+1
GDEXPSDZ1 |
Faculty of Pharmacy in Hradec Králové
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Publications
publication
S-Nitrosoglutathione covalently modifies cysteine residues of human carbonyl reductase 1 and affects its activity
2013 |
Faculty of Pharmacy in Hradec Králové
publication
Salicylanilide derivatives block Mycobacterium tuberculosis through inhibition of isocitrate lyase and methionine aminopeptidase
2012 |
Faculty of Pharmacy in Hradec Králové
publication
Bruton's Tyrosine Kinase Inhibitor Zanubrutinib Effectively Modulates Cancer Resistance by Inhibiting Anthracycline Metabolism and Efflux
2022 |
Faculty of Pharmacy in Hradec Králové
publication
Isocitrate dehydrogenase 2 inhibitor enasidenib synergizes daunorubicin cytotoxicity by targeting aldo-keto reductase 1C3 and ATP-binding cassette transporters
2022 |
Faculty of Pharmacy in Hradec Králové
publication
Inhibition of AKR1B10-mediated metabolism of daunorubicin as a novel off-target effect for the Bcr-Abl tyrosine kinase inhibitor dasatinib
2021 |
Faculty of Pharmacy in Hradec Králové
publication
Selective inhibition of aldo-keto reductase 1C3: a novel mechanism involved in midostaurin and daunorubicin synergism
2021 |
Faculty of Pharmacy in Hradec Králové
publication
Targeting Pharmacokinetic Drug Resistance in Acute Myeloid Leukemia Cells with CDK4/6 Inhibitors
2020 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Olaparib Synergizes the Anticancer Activity of Daunorubicin via Interaction with AKR1C3
2020 |
Faculty of Pharmacy in Hradec Králové
publication
Interactions of antileukemic drugs with daunorubicin reductases: could reductases affect the clinical efficacy of daunorubicin chemoregimens?
2020 |
Faculty of Pharmacy in Hradec Králové
publication
Bruton's Tyrosine Kinase Inhibitors Ibrutinib and Acalabrutinib Counteract Anthracycline Resistance in Cancer Cells Expressing AKR1C3
2020 |
Faculty of Pharmacy in Hradec Králové
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