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cytotoxicity
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doc. RNDr. Jakub Hofman Ph.D.
Academic staff at Faculty of Pharmacy in Hradec Králové
3 classes
37 publications
Classes
class
Current Strategies in Pharmacotherapy
GAF360 |
Faculty of Pharmacy in Hradec Králové
class
Current strategies in pharmacotherapy
+1
GAPS016 |
Faculty of Pharmacy in Hradec Králové
Publications
publication
Sonidegib potentiates the cancer cells' sensitivity to cytostatic agents by functional inhibition of ABCB1 and ABCG2 in vitro and ex vivo
2022 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Dabrafenib inhibits ABCG2 and cytochrome P450 isoenzymes; potential implications for combination anticancer therapy
2022 |
Faculty of Pharmacy in Hradec Králové
publication
Isocitrate dehydrogenase 2 inhibitor enasidenib synergizes daunorubicin cytotoxicity by targeting aldo-keto reductase 1C3 and ATP-binding cassette transporters
2022 |
Faculty of Pharmacy in Hradec Králové
publication
Roles of CYP3A4, CYP3A5 and CYP2C8 drug-metabolizing enzymes in cellular cytostatic resistance
2021 |
Faculty of Pharmacy in Hradec Králové
publication
Buparlisib is a novel inhibitor of daunorubicin reduction mediated by aldo-keto reductase 1C3
2019 |
Faculty of Pharmacy in Hradec Králové
publication
Inhibition of human anthracycline reductases by emodin - A possible remedy for anthracycline resistance
2016 |
Faculty of Pharmacy in Hradec Králové
publication
Flavones Inhibit the Activity of AKR1B10, a Promising Therapeutic Target for Cancer Treatment
2015 |
Faculty of Pharmacy in Hradec Králové
publication
Isoquinoline alkaloids as a novel type of AKR1C3 inhibitors
2014 |
Faculty of Pharmacy in Hradec Králové
publication
Anthracycline resistance mediated by reductive metabolism in cancer cells: The role of aldo-keto reductase 1C3
2014 |
Faculty of Pharmacy in Hradec Králové
publication
Purvalanol A, Olomoucine II and Roscovitine Inhibit ABCB1 Transporter and Synergistically Potentiate Cytotoxic Effects of Daunorubicin In Vitro
2013 |
Faculty of Pharmacy in Hradec Králové
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