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genotoxic mechanism
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RNDr. Karel Naiman Ph.D.
External academic staff at Faculty of Science
8 publications
Publications
publication
Formation, Persistence, and Identification of DNA Adducts Formed by the Carcinogenic Environmental Pollutant o-Anisidine in Rats
2012 |
Faculty of Science, Central Library of Charles University
publication
Genotoxic mechanisms for the carcinogenicity of the environmental pollutants and carcinogens o-anisidine and 2-nitroanisole follow from adducts generated by their metabolite N-(2-methoxyphenyl)-hydroxylamine with deoxyguanosine in DNA
2009 |
Faculty of Science, First Faculty of Medicine, Faculty of Mathematics and Physics
publication
Redox cycling in the metabolism of the environmental pollutant and suspected human carcinogen o-anisidine by rat and rabbit hepatic microsomes
2008 |
Faculty of Science, Central Library of Charles University
publication
Human cytochrome-P450 enzymes metabolize N-(2-methoxyphenyl)hydroxylamine, a metabolite of the carcinogens o-anisidine and o-nitroanisole, thereby dictating its genotoxicity
2011 |
Faculty of Science
publication
Rat liver microsomal metabolism of o-aminophenol and N-(2-methoxyphenyl)hydroxylamine, two metabolites of the environmental pollutant and carcinogen o-anisidine in humans
2010 |
Faculty of Science
publication
Identification of rat cytochromes P450 metabolizing N-(2-methoxyphenyl)hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o- nitroanisole
2010 |
Faculty of Science
publication
Isolation and partial characterization of the adduct formed by 13-hydroxyellipticine with deoxyguanosine in DNA
2008 |
Faculty of Science
publication
Cytochrome P450-mediated metabolism of N-(2-methoxyphenyl)-hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole
2008 |
Faculty of Science
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