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prof. MUDr. Tomáš Eckschlager CSc.
Academic staff at Second Faculty of Medicine
330 publications
Publications
publication
Electrochemical Determination of Enzymes Metabolizing Ellipticine in Thyroid Cancer Cells - a Tool to Explain the Mechanism of Ellipticine Toxicity to these Cells
2013 |
Faculty of Science, Second Faculty of Medicine
publication
Mechanisms of ellipticine-mediated resistance in UKF-NB-4 neuroblastoma cells
2012 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport, Second Faculty of Medicine
publication
Metallothioneins and zinc in cancer diagnosis and therapy
2012 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport, Second Faculty of Medicine
publication
Impact of histone deacetylase inhibitor valproic acid on the anticancer effect of etoposide on neuroblastoma cells
2012 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport, Second Faculty of Medicine
publication
Cytochrome b(5) Increases Cytochrome P450 3A4-Mediated Activation of Anticancer Drug Ellipticine to 13-Hydroxyellipticine Whose Covalent Binding to DNA Is Elevated by Sulfotransferases and N,O-Acetyltransferases
2012 |
Faculty of Science, Second Faculty of Medicine
publication
Ellipticine cytotoxicity to cancer cell lines - a comparative study
2011 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Clinical importance of matrix metalloproteinases
2011 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Assays for determination of matrix metalloproteinases and their activity
2011 |
Faculty of Science, First Faculty of Medicine, Faculty of Physical Education and Sport
publication
Mammalian peroxidases activate anticancer drug ellipticine to intermediates forming deoxyguanosine adducts in DNA identical to those found in vivo and generated from 12-hydroxyellipticine and 13-hydroxyellipticine
2007 |
Faculty of Science, Second Faculty of Medicine, Central Library of Charles University
publication
DNA adduct formation by the anticancer drug ellipticine in human leukemia HL-60 and CCRF-CEM cells
2007 |
Faculty of Science, Second Faculty of Medicine
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