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prof. PharmDr. Jana Žďárová Karasová Ph.D.
External academic staff at Faculty of Medicine in Hradec Králové
44 publications
Publications
publication
Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition
2024 |
Faculty of Science, First Faculty of Medicine, Third Faculty of Medicine
publication
The measured CSF/plasma donepezil concentration ratio but not individually measured CSF and plasma concentrations significantly increase over 24 h after donepezil treatment in patients with Alzheimer's disease
2023 |
Faculty of Medicine in Hradec Králové, Second Faculty of Medicine
publication
Determination of K869, a Novel Oxime Reactivator of Acetylcholinesterase, in Rat Body Fluids and Tissues by Liquid-Chromatography Methods: Pharmacokinetic Study
2021 |
Faculty of Pharmacy in Hradec Králové
publication
Development of versatile and potent monoquaternary reactivators of acetylcholinesterase
2021 |
Publication without faculty affiliation
publication
The New Acetylcholinesterase Inhibitors PC-37 and PC-48 (7-Methoxytacrine-Donepezil-Like Compounds): Characterization of Their Metabolites in Human Liver Microsomes, Pharmacokinetics and In Vivo Formation of the Major Metabolites in Rats
2018 |
Faculty of Medicine in Hradec Králové
publication
A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase
2018 |
Publication without faculty affiliation
publication
Development of small bisquaternary cholinesterase inhibitors as drugs for pre-treatment of nerve agent poisonings
2018 |
Publication without faculty affiliation
publication
1-Benzyl-4-methylpiperidinyl moiety in donepezil: The priority ticket across the blood-brain-barrier in rats
2018 |
Publication without faculty affiliation
publication
Concentration of Donepezil in the Cerebrospinal Fluid of AD Patients: Evaluation of Dosage Sufficiency in Standard Treatment Strategy
2017 |
Faculty of Medicine in Hradec Králové, Second Faculty of Medicine
publication
Activity of cholinesterases in a young and healthy middle-European population: Relevance for toxicology, pharmacology and clinical praxis
2017 |
Publication without faculty affiliation
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