External academic staff at Faculty of Medicine in Hradec Králové
Publications
- The measured CSF/plasma donepezil concentration ratio but not individually measured CSF and plasma concentrations significantly increase over 24 h after donepezil treatment in patients with Alzheimer's disease2023 | Faculty of Medicine in Hradec Králové, Second Faculty of Medicine
- The effect of single and repeated doses of rivastigmine on gastric myoelectric activity in experimental pigs2023 | Faculty of Medicine in Hradec Králové, First Faculty of Medicine
- Tacrine and its 7-methoxy derivate; time-change concentration in plasma and brain tissue and basic toxicological profile in rats2021 | Faculty of Medicine in Hradec Králové
- Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease2021 | Publication without faculty affiliation
- Donepezil and Rivastigmine: Pharmacokinetic profile and brain-targeting after intramuscular administration in rats2020 | Publication without faculty affiliation
- UHPLC-HRMS study of anti-Alzheimer's drug candidates: metabolism of 7-MEOTA-tryptophan hybrids hampers their passage into brain2019 | Faculty of Medicine in Hradec Králové
- The New Acetylcholinesterase Inhibitors PC-37 and PC-48 (7-Methoxytacrine-Donepezil-Like Compounds): Characterization of Their Metabolites in Human Liver Microsomes, Pharmacokinetics and In Vivo Formation of the Major Metabolites in Rats2018 | Faculty of Medicine in Hradec Králové
- Development of small bisquaternary cholinesterase inhibitors as drugs for pre-treatment of nerve agent poisonings2018 | Publication without faculty affiliation
- An HPLC-MS method for the quantification of new acetylcholinesterase inhibitor PC 48 (7-MEOTA-donepezil like compound) in rat plasma: Application to a pharmacokinetic study2016 | Publication without faculty affiliation
- Cholinergic properties of new 7-methoxytacrine-donepezil derivatives2015 | Faculty of Science
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