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Blood-brain barrier
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prof. PharmDr. Jana Žďárová Karasová Ph.D.
External academic staff at Faculty of Medicine in Hradec Králové
44 publications
Publications
publication
UHPLC-HRMS study of pharmacokinetics of a novel hybrid cholinesterase inhibitor K1234: A comparison between in silico, in vitro and in vivo data
2022 |
Faculty of Medicine in Hradec Králové
publication
Tacrine and its 7-methoxy derivate; time-change concentration in plasma and brain tissue and basic toxicological profile in rats
2021 |
Faculty of Medicine in Hradec Králové
publication
In vitro and in vivo metabolism of 3-quinuclidinyl benzilate by high-resolution mass spektrometry
2020 |
Faculty of Medicine in Hradec Králové
publication
Interaction of Cucurbit[7]uril with Oxime K027, Atropine, and Paraoxon: Risky or advantageous delivery system?
2020 |
Faculty of Medicine in Hradec Králové
publication
Encapsulation of oxime K027 into cucurbit[7]uril: In vivo evaluation of safety, absorption, brain distribution and reactivation effectiveness
2020 |
Publication without faculty affiliation
publication
Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease
2019 |
Faculty of Medicine in Hradec Králové, Central Library of Charles University
publication
UHPLC-HRMS study of anti-Alzheimer's drug candidates: metabolism of 7-MEOTA-tryptophan hybrids hampers their passage into brain
2019 |
Faculty of Medicine in Hradec Králové
publication
Characterization of the penetration of the blood-brain barrier by high-performance liquid chromatography (HPLC) using a stationary phase with an immobilized artificial membrane
2018 |
Faculty of Education
publication
1-Benzyl-4-methylpiperidinyl moiety in donepezil: The priority ticket across the blood-brain-barrier in rats
2018 |
Publication without faculty affiliation
publication
Concentration of Donepezil in the Cerebrospinal Fluid of AD Patients: Evaluation of Dosage Sufficiency in Standard Treatment Strategy
2017 |
Faculty of Medicine in Hradec Králové, Second Faculty of Medicine
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