External academic staff at Faculty of Medicine in Hradec Králové
Publications
- UHPLC-HRMS study of pharmacokinetics of a novel hybrid cholinesterase inhibitor K1234: A comparison between in silico, in vitro and in vivo data2022 | Faculty of Medicine in Hradec Králové
- The Impact of Dextran Sodium Sulfate-Induced Gastrointestinal Injury on the Pharmacokinetic Parameters of Donepezil and Its Active Metabolite 6-O-desmethyldonepezil, and Gastric Myoelectric Activity in Experimental Pigs2021 | Faculty of Medicine in Hradec Králové, Faculty of Pharmacy in Hradec Králové
- Encapsulation of oxime K027 into cucurbit[7]uril: In vivo evaluation of safety, absorption, brain distribution and reactivation effectiveness2020 | Publication without faculty affiliation
- The New Acetylcholinesterase Inhibitors PC-37 and PC-48 (7-Methoxytacrine-Donepezil-Like Compounds): Characterization of Their Metabolites in Human Liver Microsomes, Pharmacokinetics and In Vivo Formation of the Major Metabolites in Rats2018 | Faculty of Medicine in Hradec Králové
- Pharmacokinetic profile of promising acetylcholinesterase reactivators K027 and K203 in experimental pigs2017 | Faculty of Medicine in Hradec Králové
- Small Quaternary Inhibitors K298 and K524: Cholinesterases Inhibition, Absorption, Brain Distribution, and Toxicity2016 | Faculty of Medicine in Hradec Králové
- HI-6 oxime (an acetylcholinesterase reactivator): blood plasma pharmacokinetics and organ distribution in experimental pigs2014 | Faculty of Medicine in Hradec Králové
- Entry of oxime K027 into the different parts of rat brain: Comparison with obidoxime and oxime HI-62014 | Publication without faculty affiliation
- Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition2024 | Faculty of Science, First Faculty of Medicine, Third Faculty of Medicine
- The measured CSF/plasma donepezil concentration ratio but not individually measured CSF and plasma concentrations significantly increase over 24 h after donepezil treatment in patients with Alzheimer's disease2023 | Faculty of Medicine in Hradec Králové, Second Faculty of Medicine
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