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Tacrine
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prof. PharmDr. Jana Žďárová Karasová Ph.D.
External academic staff at Faculty of Medicine in Hradec Králové
44 publications
Publications
publication
Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition
2024 |
Faculty of Science, First Faculty of Medicine, Third Faculty of Medicine
publication
Tacrine and its 7-methoxy derivate; time-change concentration in plasma and brain tissue and basic toxicological profile in rats
2021 |
Faculty of Medicine in Hradec Králové
publication
Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease
2021 |
Publication without faculty affiliation
publication
Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease
2019 |
Faculty of Medicine in Hradec Králové, Central Library of Charles University
publication
The New Acetylcholinesterase Inhibitors PC-37 and PC-48 (7-Methoxytacrine-Donepezil-Like Compounds): Characterization of Their Metabolites in Human Liver Microsomes, Pharmacokinetics and In Vivo Formation of the Major Metabolites in Rats
2018 |
Faculty of Medicine in Hradec Králové
publication
The measured CSF/plasma donepezil concentration ratio but not individually measured CSF and plasma concentrations significantly increase over 24 h after donepezil treatment in patients with Alzheimer's disease
2023 |
Faculty of Medicine in Hradec Králové, Second Faculty of Medicine
publication
The effect of single and repeated doses of rivastigmine on gastric myoelectric activity in experimental pigs
2023 |
Faculty of Medicine in Hradec Králové, First Faculty of Medicine
publication
Effect of ketamine, an NMDA-receptor antagonist, on gastric myoelectric activity in experimental pigs
2022 |
Faculty of Medicine in Hradec Králové, First Faculty of Medicine
publication
UHPLC-HRMS study of pharmacokinetics of a novel hybrid cholinesterase inhibitor K1234: A comparison between in silico, in vitro and in vivo data
2022 |
Faculty of Medicine in Hradec Králové
publication
A systematic evaluation of the cucurbit[7]uril pharmacokinetics and toxicity after a single dose and short-term repeated administration in mice
2022 |
Publication without faculty affiliation
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