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Studium
RNDr. Eva Novotná Ph.D.
Akademický pracovník na Farmaceutická fakulta v Hradci Králové
63 publikací
Publikace
publication
Cyclin-dependent kinase inhibitors AZD5438 and R547 show potential for enhancing efficacy of daunorubicin-based anticancer therapy: Interaction with carbonyl-reducing enzymes and ABC transporters
2019 |
Farmaceutická fakulta v Hradci Králové
publication
Interactions of Alectinib with Human ATP-Binding Cassette Drug Efflux Transporters and Cytochrome P450 Biotransformation Enzymes: Effect on Pharmacokinetic Multidrug Resistance
2019 |
Farmaceutická fakulta v Hradci Králové
publication
Buparlisib is a novel inhibitor of daunorubicin reduction mediated by aldo-keto reductase 1C3
2019 |
Farmaceutická fakulta v Hradci Králové
publication
Aldo-keto reductase 1C3 (AKR1C3): a missing piece of the puzzle in the dinaciclib interaction profile
2018 |
Farmaceutická fakulta v Hradci Králové
publication
Roscovitine and purvalanol A effectively reverse anthracycline resistance mediated by the activity of aldo-keto reductase 1C3 (AKR1C3): A promising therapeutic target for cancer treatment
2018 |
Farmaceutická fakulta v Hradci Králové
publication
Tazemetostat synergistically combats multidrug resistance by the unique triple inhibition of ABCB1, ABCC1, and ABCG2 efflux transporters in vitro and ex vivo
2023 |
Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
publication
Talazoparib Does Not Interact with ABCB1 Transporter or Cytochrome P450s, but Modulates Multidrug Resistance Mediated by ABCC1 and ABCG2: An in Vitro and Ex Vivo Study
2022 |
Farmaceutická fakulta v Hradci Králové, Lékařská fakulta v Hradci Králové
publication
Alisertib shows negligible potential for perpetrating pharmacokinetic drug-drug interactions on ABCB1, ABCG2 and cytochromes P450, but acts as dual-activity resistance modulator through the inhibition of ABCC1 transporter
2022 |
Farmaceutická fakulta v Hradci Králové
publication
Substituted N-phenylitaconamides as inhibitors of mycobacteria and mycobacterial isocitrate lyase
2022 |
Farmaceutická fakulta v Hradci Králové
publication
Bruton's Tyrosine Kinase Inhibitor Zanubrutinib Effectively Modulates Cancer Resistance by Inhibiting Anthracycline Metabolism and Efflux
2022 |
Farmaceutická fakulta v Hradci Králové
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