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Enzymes
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RNDr. Eva Novotná Ph.D.
Academic staff at Faculty of Pharmacy in Hradec Králové
63 publications
Publications
publication
Targeting Pharmacokinetic Drug Resistance in Acute Myeloid Leukemia Cells with CDK4/6 Inhibitors
2020 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Initial characterization of human DHRS1 (SDR19C1), a member of the short chain dehydrogenase/reductase superfamily
2019 |
Faculty of Pharmacy in Hradec Králové, Faculty of Medicine in Hradec Králové
publication
Cyclin-dependent kinase inhibitors AZD5438 and R547 show potential for enhancing efficacy of daunorubicin-based anticancer therapy: Interaction with carbonyl-reducing enzymes and ABC transporters
2019 |
Faculty of Pharmacy in Hradec Králové
publication
Interactions of Alectinib with Human ATP-Binding Cassette Drug Efflux Transporters and Cytochrome P450 Biotransformation Enzymes: Effect on Pharmacokinetic Multidrug Resistance
2019 |
Faculty of Pharmacy in Hradec Králové
publication
Buparlisib is a novel inhibitor of daunorubicin reduction mediated by aldo-keto reductase 1C3
2019 |
Faculty of Pharmacy in Hradec Králové
publication
Phenolic N-monosubstituted carbamates: Antitubercular and toxicity evaluation of multi-targeting compounds
2019 |
Faculty of Pharmacy in Hradec Králové
publication
Aldo-keto reductase 1C3 (AKR1C3): a missing piece of the puzzle in the dinaciclib interaction profile
2018 |
Faculty of Pharmacy in Hradec Králové
publication
Roscovitine and purvalanol A effectively reverse anthracycline resistance mediated by the activity of aldo-keto reductase 1C3 (AKR1C3): A promising therapeutic target for cancer treatment
2018 |
Faculty of Pharmacy in Hradec Králové
publication
Design, Synthesis, and Biological Evaluation of Isothiosemicarbazones with Antimycobacterial Activity
2017 |
Faculty of Pharmacy in Hradec Králové
publication
Flavones Inhibit the Activity of AKR1B10, a Promising Therapeutic Target for Cancer Treatment
2015 |
Faculty of Pharmacy in Hradec Králové
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