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Ellipticine
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RNDr. Dagmar Svášková Ph.D.
Academic staff at Faculty of Science
25 publications
Publications
publication
Induced Expression of Cytochrome P450 1A and NAD(P)H:Quinone Oxidoreductase Determined at mRNA, Protein, and Enzyme Activity Levels in Rats Exposed to the Carcinogenic Azo Dye 1-Phenylazo-2-naphthol (Sudan I)
2013 |
Faculty of Science
publication
Ellipticine and benzo(a)pyrene increase their own metabolic activation via modulation of expression and enzymatic activity of cytochromes P450 1A1 and 1A2
2008 |
Faculty of Science
publication
Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice
2008 |
Faculty of Science
publication
DNA adduct formation by the anticancer drug ellipticine in human leukemia HL-60 and CCRF-CEM cells
2007 |
Faculty of Science, Second Faculty of Medicine
publication
Formation and persistence of DNA adducts of anticancer drug ellipticine in rats
2007 |
Faculty of Science
publication
The anticancer drug ellipticine is a potent inducer of rat cytochromes P450 1A1 and 1A2, thereby modulating its own metabolism
2007 |
Faculty of Science
publication
The anticancer drug ellipticine is an inducer of rat NAD(P)H : Quinone oxidoreductase
2007 |
Faculty of Science
publication
Cytochromes P450 reconstituted with NADPH:P450 reductase mimic the activating and detoxicating metabolism of the anticancer drug ellipticine in microsomes
2006 |
Faculty of Science
publication
Oxidation pattern of the anticancer drug ellipticine by hepatic microsomes - Similarity between human and rat systems
2006 |
Faculty of Science
publication
Antitumor drug ellipticine inhibits the activities of rat hepatic cytochromes P450
2005 |
Faculty of Science
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