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Enzymes
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RNDr. Dagmar Svášková Ph.D.
Academic staff at Faculty of Science
25 publications
Publications
publication
Induced Expression of Cytochrome P450 1A and NAD(P)H:Quinone Oxidoreductase Determined at mRNA, Protein, and Enzyme Activity Levels in Rats Exposed to the Carcinogenic Azo Dye 1-Phenylazo-2-naphthol (Sudan I)
2013 |
Faculty of Science
publication
Ellipticine and benzo(a)pyrene increase their own metabolic activation via modulation of expression and enzymatic activity of cytochromes P450 1A1 and 1A2
2008 |
Faculty of Science
publication
DNA adduct formation by the anticancer drug ellipticine in human leukemia HL-60 and CCRF-CEM cells
2007 |
Faculty of Science, Second Faculty of Medicine
publication
Formation and persistence of DNA adducts of anticancer drug ellipticine in rats
2007 |
Faculty of Science
publication
The anticancer drug ellipticine is a potent inducer of rat cytochromes P450 1A1 and 1A2, thereby modulating its own metabolism
2007 |
Faculty of Science
publication
The anticancer drug ellipticine is an inducer of rat NAD(P)H : Quinone oxidoreductase
2007 |
Faculty of Science
publication
The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N-2-oxide
2004 |
Faculty of Science
publication
ANTICANCER DRUG ELLIPTICINE ACTS AS AN INDUCER OF CYTOCHROMES P450 1A1/2 AND POTENTIATES ITS OWN PHARMACOLOGICAL EFFICIENCY
2003 |
Faculty of Science
publication
The anticancer drug ellipticine acts as an inducer of cytochromes P450 1A1/2 and potentiates its own pharmacological efficiency
2003 |
Faculty of Science
publication
Preparation of a biologically active apo-cytochrome b5 via heterologous expression in Escherichia coli
2009 |
Faculty of Science
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