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antiviral resistance
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Mgr. Klára Grantz Šašková Ph.D.
Academic staff at Faculty of Science
1 class
34 publications
Class
class
Antiviral Drug Discovery
MB140P97 |
Faculty of Science
Publications
publication
GS-8374, a Prototype Phosphonate-Containing Inhibitor of HIV-1 Protease, Effectively Inhibits Protease Mutants with Amino Acid Insertions
2014 |
Faculty of Science
publication
Inorganic polyhedral metallacarborane inhibitors of HIV protease: A new approach to overcoming antiviral resistance.
2008 |
Faculty of Science
publication
Molecular analysis of the HIV-1 resistance development: enzymatic activities, crystal structures, and thermodynamics of nelfinavir-resistant HIV protease mutants
2007 |
Faculty of Science
publication
Discovery of the activators of NRF1 pathway affecting proteasome activity and preventing protein aggregation
2023 |
Faculty of Science, Central Library of Charles University
publication
Small molecules affecting proteasome activity and heat shock response for clearance of toxic protein species
2022 |
Faculty of Science, Faculty of Physical Education and Sport, Central Library of Charles University, First Faculty of Medicine, Faculty of Mathematics and Physics
publication
Lipid Nanoparticles for Broad-Spectrum Nucleic Acid Delivery
2021 |
Faculty of Science, Faculty of Physical Education and Sport, Central Library of Charles University, First Faculty of Medicine
publication
Nelfinavir Inhibits the TCF11/Nrf1-Mediated Proteasome Recovery Pathway in Multiple Myeloma
2020 |
Faculty of Science, Faculty of Physical Education and Sport, First Faculty of Medicine
publication
Capturing a dynamically interacting inhibitor by paramagnetic NMR spectroscopy
2019 |
Faculty of Science
publication
The yeast proteases Ddi1 and Wss1 are both involved in the DNA replication stress response
2019 |
Faculty of Science
publication
Quantitative proteomics reveals neuronal ubiquitination of Rngo/Ddi1 and several proteasomal subunits by Ube3a, accounting for the complexity of Angelman syndrome
2018 |
Faculty of Science, Faculty of Physical Education and Sport
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