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protease inhibitors
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Mgr. Klára Grantz Šašková Ph.D.
Academic staff at Faculty of Science
1 class
34 publications
Class
class
Antiviral Drug Discovery
MB140P97 |
Faculty of Science
Publications
publication
Nelfinavir Inhibits the TCF11/Nrf1-Mediated Proteasome Recovery Pathway in Multiple Myeloma
2020 |
Faculty of Science, Faculty of Physical Education and Sport, First Faculty of Medicine
publication
Thermodynamic and structural analysis of HIV protease resistance to darunavir - analysis of heavily mutated patient- derived HIV-1 proteases
2014 |
Faculty of Science
publication
Mutations in HIV-1 gag and pol compensate for the loss of viral fitness caused by a highly mutated protease
2012 |
Faculty of Science
publication
Design of HIV protease inhibitors based on inorganic polyhedral metallacarboranes
2009 |
Faculty of Science
publication
Molecular Characterization of Clinical Isolates of Human Immunodeficiency Virus Resistant to the Protease Inhibitor Darunavir
2009 |
Faculty of Science
publication
Ninety-nine is not enough: Molecular characterization of inhibitor-resistant human immunodeficiency virus type 1 protease mutants with insertions in the flap region
2008 |
Faculty of Science
publication
Enzymatic and structural analysis of the I47A mutation contributing to the reduced susceptibility to HIV protease inhibitor lopinavir.
2008 |
Faculty of Science
publication
Molecular analysis of the HIV-1 resistance development: enzymatic activities, crystal structures, and thermodynamics of nelfinavir-resistant HIV protease mutants
2007 |
Faculty of Science
publication
Discovery of the activators of NRF1 pathway affecting proteasome activity and preventing protein aggregation
2023 |
Faculty of Science, Central Library of Charles University
publication
Small molecules affecting proteasome activity and heat shock response for clearance of toxic protein species
2022 |
Faculty of Science, Faculty of Physical Education and Sport, Central Library of Charles University, First Faculty of Medicine, Faculty of Mathematics and Physics
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