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Breast cancer
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Mgr. Jan Ševčík Ph.D.
Academic staff at First Faculty of Medicine
35 publications
Publications
publication
Identification of deleterious germline CHEK2 mutations and their association with breast and ovarian cancer
2019 |
First Faculty of Medicine
publication
Germline CHEK2 Gene Mutations in Hereditary Breast Cancer Predisposition - Mutation Types and their Biological and Clinical Relevance
2019 |
First Faculty of Medicine
publication
BRCA1 and BRCA2 5 ' noncoding region variants identified in breast cancer patients alter promoter activity and protein binding
2018 |
First Faculty of Medicine
publication
Mutation analysis of the PALB2 gene in unselected pancreatic cancer patients in the Czech Republic
2016 |
First Faculty of Medicine
publication
Expression of human BRCA1 Delta 17-19 alternative splicing variant with a truncated BRCT domain in MCF-7 cells results in impaired assembly of DNA repair complexes and aberrant DNA damage response
2013 |
First Faculty of Medicine, Third Faculty of Medicine
publication
The BRCA1 alternative splicing variant Delta 14-15 with an in-frame deletion of part of the regulatory serine-containing domain (SCD) impairs the DNA repair capacity in MCF-7 cells
2012 |
First Faculty of Medicine, Third Faculty of Medicine
publication
Establishment, growth and in vivo differentiation of a new clonal human cell line, EM-G3, derived from breast cancer progenitors
2007 |
First Faculty of Medicine, Central Library of Charles University, Faculty of Physical Education and Sport
publication
The new cell line, EM-G3, derived from breast cancer progenitors
Publication without faculty affiliation
publication
System of in vitro analysis of BRCA1 sequence variants in patients with hereditary breast cancer
Publication without faculty affiliation
publication
Higher frequency of non-conservative mutations in fork-head associated (FHA) domain of checkpoint kinase 2 (CHEK2) gene in breast cancer patients
Publication without faculty affiliation
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