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Xenobiotics
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Tomáš Sklenář
External person at First Faculty of Medicine
18 publications
Publications
publication
Xenobiotic Metabolism: A View through the Metabolometer
2010 |
First Faculty of Medicine
publication
Rifampicin-Activated Human Pregnane X Receptor and CYP3A4 Induction Enhance Acetaminophen-Induced Toxicity
2009 |
First Faculty of Medicine
publication
A Double Transgenic Mouse Model Expressing Human Pregnane X Receptor and Cytochrome P450 3A4
2008 |
First Faculty of Medicine
publication
Urinary metabolomics in Fxr-null mice reveals activated adaptive metabolic pathways upon bile acid challenge
2010 |
First Faculty of Medicine
publication
Comparative metabolism of cyclophosphamide and ifosfamide in the mouse using UPLC-ESI-QT0FMS-based metabolomics
2010 |
First Faculty of Medicine
publication
Analysis of N1-acetyl-N2-formyl-5-methoxykynuramine/N1-acetyl-5-methoxy-kynuramine formation from melatonin in mice
2010 |
First Faculty of Medicine
publication
Control of Steroid 21-oic Acid Synthesis by Peroxisome Proliferator-activated Receptor alpha and Role of the Hypothalamic-Pituitary-Adrenal Axis
2010 |
First Faculty of Medicine
publication
Identification of Noninvasive Biomarkers for Alcohol-Induced Liver Disease Using Urinary Metabolomics and the Ppara-null Mouse
2010 |
First Faculty of Medicine
publication
Serum Metabolomics Reveals Irreversible Inhibition of Fatty Acid beta-Oxidation through the Suppression of PPAR alpha Activation as a Contributing Mechanism of Acetaminophen-Induced Hepatotoxicity
2009 |
First Faculty of Medicine
publication
Metabolomics reveals a novel vitamin E metabolite and attenuated vitamin E metabolism upon PXR activation
2009 |
First Faculty of Medicine
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