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acetaminophen
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Tomáš Sklenář
External person at First Faculty of Medicine
18 publications
Publications
publication
Serum Metabolomics Reveals Irreversible Inhibition of Fatty Acid beta-Oxidation through the Suppression of PPAR alpha Activation as a Contributing Mechanism of Acetaminophen-Induced Hepatotoxicity
2009 |
First Faculty of Medicine
publication
Rifampicin-Activated Human Pregnane X Receptor and CYP3A4 Induction Enhance Acetaminophen-Induced Toxicity
2009 |
First Faculty of Medicine
publication
Identification of novel toxicity-associated metabolites by metabolomics and mass isotopomer analysis of acetaminophen metabolism in wild-type and Cyp2e1-null mice
2008 |
First Faculty of Medicine
publication
Urinary metabolomics in Fxr-null mice reveals activated adaptive metabolic pathways upon bile acid challenge
2010